Current Research

Mitochondria stained using TMRM. These are neonatal rat cardiomyocytes cultured on PDMS for 5 days without any alignment and using fibronectin coating.
Mitochondria stained using TMRM. These are neonatal rat cardiomyocytes cultured on PDMS for 5 days without any alignment and using fibronectin coating.

Currently, I am working under supervision of Dr. Megan McCain at the Laboratory for Living Systems Engineering. My project focus on the comparison of the structure and function of mitochondria in engineered cardiac tissues as a function of matrix stiffness. The project uses tissue engineering, microscopy, biomaterials and image processing techniques to determine how extracellular matrix stiffness regulates the structure and function of mitochondria in cardiac myocytes. Further research will also evaluate metabolic and genetic responses to different matrix properties.

For more information, consult my publications or contact me.